Study population and setting
Using data on current case numbers and interventions, authors modified a Susceptible-Exposed-Contagious-Infected-Recovered (SECIR) compartmental model to predict the total number of severe COVID-19 cases for 52 African countries. Then, using these projections, authors estimated the number of hospital beds, ICU beds, and ventilators needed at the peak of the outbreak per country assuming four levels of care-seeking behavior (if 30, 50, 70, or 100% of patients with severe COVID-19 symptoms sought care). Authors assumed that interventions would decrease transmission by 25% while implemented, but would return to 90% of the pre-intervention value after being lifted. Although they did not explicitly account for age and comorbidities in the model, authors did include these parameters as a function of the projected number of people who would develop severe disease.
Summary of Main Findings
The average number of total projected severe cases per country was 138 per 100,000 (this ranged from 102 per 100,000 to 145 per 100,000). Assuming the most burdensome care volume (i.e., 100% of persons with severe infection sought care), an average of 131.7 per 100,000 hospital beds, 6.5 per 100,000 ICU beds, and 3.18 per 100,000 ventilators would be needed. Authors estimated that 62% of countries do not have enough hospital beds to meet this need and that some countries would require up to 10,000 additional beds. Authors estimated that over 87% of countries do not have sufficient ICU beds to handle the projected number of severe cases and that countries would require 5,000 to 12,000 additional ICU beds. Authors estimated that over 91% of countries do not have enough ventilators to meet national needs. Assuming the least burdensome care volume (i.e., 30% seek care), authors still estimated that 20%, 71%, and 76% of countries could not meet hospital bed, ICU bed, and ventilator needs.
Authors used current case numbers and specific interventions per country, so estimates are country-specific.
Authors assumed that all resources (hospital beds, ICU beds, and ventilators) would be functional and immediately available for first use by COVID-19 patients. This discounts the consumption of these resources by other patients hospitalized for non-COVID-19 related reasons and likely overestimates each country’s true capacity. Authors also assumed hospital beds, ICU beds, and ventilators were distributed evenly throughout each country’s population; these resources are often clustered in urban areas and this overestimates the availability of these resources to populations in more rural areas, which also likely overestimates national capacity. Authors used case severity data from China, Europe, and the US; studies that have since been released suggest that case severity may differ considerably in African countries, which have younger age distributions and different contact patterns and potential exposures.
As confirmed COVID-19 cases and deaths continue to increase across the African continent, critical care capacity, gaps, and needs should be assessed to inform pandemic planning and preparation. This study is among the first to provide a comprehensive assessment of these parameters across Africa.
This review was posted on: 15 September 2020